
ligand-detargeted lentiviral payloads
When these bespoke envelopes are co-packaged with ligand-detargeted lentiviral payloads (bearing codon-optimized gag-pol, cPPT/CTS hyper-loop, and lineage-specific miR silencing cassettes), the progeny reach supranuclear titers, negligible RCL background noise, and integration landscapes that crescendo within target chromatin yet fall silent in non-selected cells.
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